HORDB

ID: hor002011
Uniprot ID: F5XVF4
Protein name: t-GnRH-6
Gene name: NA
Organism: Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Family: GnRH family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Ciona (genus), Cionidae (family), Phlebobranchia (order), Ascidiacea (class), Tunicata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: NA
GO CC: NA

Sequence: WLRYDA
Length: 6(162-167)
Propeptide: MKNIFLVSVLIFAYQSTTLADDPHSMNTRGRVDPRKEFCNELINGGRVGFSMIQQLCGSYGKRMFSRTRTTRNEPIVTSRRSGSALPEAMMSDDTFNTRGSYNGRKTSYRTGRRPEHELVSRLAAALRRQFSSVTKHSNFDRPKDDWRVRDTDGPMYLIKKWLRYDA
Signal peptide: MKNIFLVSVLIFAYQSTTLA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Function: NA
Mechanism: The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002011_AF2.pdb

hor002011_ESM.pdb

Mass:	91229	Formula:	C39H54N10O10
Absent amino acids:	CEFGHIKMNPQSTV	Common amino acids:	ADLRWY
pI:	6.34	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	3
Hydrophobicity:	-76.67	Boman Index:	-1472
Half-Life:	2.8 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	81.67
Instability Index:	8790	Extinction Coefficient cystines:	6990
Absorbance 280nm:	1398

PubMed ID: 21467196
Title: Peptidomic Analysis of the Central Nervous System of the Protochordate, Ciona Intestinalis: Homologs and Prototypes of Vertebrate Peptides and Novel Peptides